Optimising PharmacoTherapy In the multimorbid elderly in primary CAre is a cluster randomised controlled trial that will include outpatients from the Swiss primary care setting with polypharmacy, in order to optimize medication appropriateness.
The project makes use of the STRIP Assistant and the internationally coded STOPP-/START-criteria.
- SEPTIMAL The SEPTIMAL study aims at finding risk factors for strokes, in order to create algorithms for its prevention in patients. A wide variety of state-of-the-art machine learning techniques are employed to achieve this goal. As a researcher and data scientist, I advised in setting up the required data infrastructure and processing pipeline.
- PRESOMATIC The PRESOMATIC study aims at aiding general practitioners with the early recognition of somatic symptom disorders. As a researcher and data scientist, I created the data processing pipeline through which the hypotheses were tested.
- ELAN With the Extramural Leiden Academic Network (ELAN) we aim at making primary care data available for academic research. As ELAN's technical project leader, I designed and implemented a data infrastructure around the principles of FAIR research data management: to make data findable, accessible, interoperable, and reusable.
- OPERAM OPERAM (OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly) is an international randomized controlled trial aimed at optimizing existing pharmacological and non-pharmacological therapy primarily in order to reduce avoidable hospital admissions among the elderly population aged ≥70 years with multimorbidity. As a postdoctoral researcher, I adapted the STRIP Assistant for use in multiple countries, setting up processes for including, modeling, and validating data from multiple sources. As the lead developer, I coordinated the selection and inclusion of international and local medical standards for data integration.
- Opti-Med The Opti-Med study investigates the (cost) effectiveness and implementation of a structured medication review in elderly patients. The trial is performed in 25 general practices in Amsterdam, the Netherlands and includes 500 patients. As a researcher and developer, I transformed the trial requirements into software features and adjusted the STRIP Assistant accordingly.
- STRIP Assistant As a PhD researcher, I designed, developed, and evaluated a software application to aid general practitioners and pharmacists in performing medication reviews for elderly people. The tool was subsequently used in the Opti-Med and OPERAM studies.